I like this becasue it's self contradictory. Even though the figure's actions show it is great agony, the background is blue and peaceful. And even though there is a ready grenade in her hand, ready to explode, flowers are growing from her mind. And flowers usually connotate happiness and peace... I think O.o Maybe it is because of these contradictory images that it is causing the headache in the first place
Although I think a dart in her boob is probably the main contributor to the headache...