I usually trace reference images I find online for really complex backgrounds/architectural elements.
I can kinda-sorta manage simple perspective drawings, but anything more complex and I'm out of my league.
I have Manga Studio, but I found it a pain to use, because it takes forever to load screen tones
although this could be because my PC is really old. Instead, I do all of my line drawings on SAI, then add the text, patterns, and screen tones on Photoshop.