I don't know about South Park. Besides, it hardly the kind of thing to emulate for a kids' show!
I'm not blaming the South Park team though--they had nothing to do with THIS. It may have been internet idiots and bratty kids smashing the word around to give it cruel implications. But it's stuck with them now so it would be best (in my opinion) to drop the word and not name ponies it.
Gah, hope that makes sense.