Yep. Here are a couple of my favorites too.
Ace Ventura
The Mask
Spongebob Squarepants
Wario Land
Shantae (I think she makes a good couple with NiGHTS. Curse my fanboyism! XD)
One Piece (I think Nico Robin makes a good couple with Xellos.Curse my fanboyism! Again! XD)
Slayers (Same reason as One Piece. Once again, curse my fanboyism! XD)
Bobobo-bo Bo-bobo (Funniest anime in all time, no doubt!)